Which disease is characterized by liver inflammation and spread through blood?

Hepatitis B is a viral infection specifically known for causing liver inflammation and can be transmitted through exposure to infectious blood, such as through sharing needles, sexual contact, and from mother to child at birth. This disease leads to liver inflammation, often resulting in symptoms such as jaundice, fatigue, and abdominal pain. The significance of Hepatitis B lies not only in acute infections but also in its potential to cause chronic liver disease, including cirrhosis and liver cancer over time.

In contrast, Hepatitis A is primarily transmitted via the fecal-oral route and does not lead to chronic liver disease. HIV is a virus that leads to acquired immunodeficiency syndrome (AIDS) and, while it can also be transmitted through blood, primarily affects the immune system rather than directly causing liver inflammation. Cirrhosis is a late-stage liver disease caused by various factors, including chronic hepatitis infections, but itself is not a disease that spreads through blood; rather, it is a result of prolonged injury to the liver.

Thus, Hepatitis B is the most accurate response regarding a disease characterized by liver inflammation and spread through blood.